The area around the Annapurna massif is the most popular trek in Nepal. The central piece of this part of Nepal is the range of mountains encompassing Annapurna I along with another giant Dhaulagiri, which is located west of Annapurna I. Between two giants, runs the valley of Kali Gandaki river, the deepest gorge on the earth. Subtropical to alpine vegetation and climates are found changing with the elevation. Trekking in the region allows to explore through rhododendron forests over the foothills of these mountains while Thakali, Gurung, Magar people are predominant in the region.

Endowed with superb view of Himalayas, endlessly changing pattern of elevation and people, this region also offers a range of short lowaltitude treks around Pokhara. Trekking to Gorapani, Landrung, Ghandruk, Birethanti and Tatopani are a few popular treks apart from trekking to Poon Hill. Buddhist Monasteries and Chortens along the trekking trail against the backdrop of Annapurnas provide excellent view. Annapurna Conservation Area Project which was established in 1986 has had innovative approach to environmental protection by involving people to avoid conflict of interest.

The region's two main trails follow river valleys in relatively easy ascents: on the west side, up the Kali Gandaki River to Jomsom and Muktinath, and to the east, up the Marsyangdi River to Manang. By crossing a high but straightforward pass, the Thorung La these trails can be joined into the classic Annapurna Circuit.The Annapurna region dramatically reveals the highland/lowland frontier running across Nepal, an interface that is both geographically and culturally amazing.